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1 mo agofound 5 d ago
Principal Scientist (Comp. Bio/ML) - Director Level
What the posting is about
Lead scientific efforts to translate foundation models into real-world drug discovery workflows. Collaborate with research, product, and business teams to deliver impactful ML + biology solutions. Requires PhD in computational biology or related field with 2+ years industry experience or MSc with 5+ years experience in ML applied to transcriptomics or genomics.
Read out of the posting
Levelmid
Experience asked2+ years
EmploymentFull time
LocationLuxembourg
RemoteNot stated
Visa sponsorshipNot stated
SalaryNot published, and most postings do not
Posted2026-08-20
Found viaworkable, direct from their system
We saw it 1 month after it went up.
The posting, as the company wrote it
Employment: Full-time
Experience: Mid-Senior level
Education: Doctorate
We’re looking for a Principal Computational Scientist/Director to help translate our foundation models into impactful, real-world discovery workflows. In this role, you’ll provide scientific leadership across model evaluation and applied use cases, ensuring our work stays grounded in the most relevant challenges in drug development and translational research.
You’ll join as a senior individual contributor with leadership and strategy experience at a point where the the team scales. You will act as a key scientific partner to our research team, mentor and support junior colleagues, and work closely with Product and Business Development to turn cutting-edge biology + ML into deliverables that matter for customers.
Requirements
PhD in Computational Biology, Machine Learning, Bioinformatics, or a related field, with a strong focus on Transcriptomics OR Genomics + ML , and 2+ years of industry (non-academic) experience OR MSc in a relevant field and 5+ years of industry experience applying ML to Transcriptomics OR Genomics problems
Strong understanding of ML/AI methods for biological data (e.g., transformers, VAEs, diffusion models, classical ML )
Hands-on experience with modern ML frameworks such as PyTorch (or equivalent)
Leadership experience with small teams to work towards defined roadmaps or projects
Excellent communication skills — able to translate complex science into clear, actionable insights for technical and non-technical stakeholders
Comfortable in a fast-paced, high-iteration environment , moving quickly from prototype → experiment → insight
Strong passion for building at the intersection of biology and machine learning
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Also open at Helical
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